"How is Your Day?": Plasma Donors Save Lives

"How is Your Day?" For all of us, this is an ordinary question we ask others – and are asked by others – every day. But for so many people around the world living with rare diseases and who rely on the availability of plasma protein therapies, no day is ordinary.

”How Is Your Day?” raises awareness of the plasma protein therapies and the value they provide to patients. It aims to inform and educate decision makers and the general public worldwide. 

Join us

”How Is Your Day?” is open to all interested people, groups, and organizations. If you have a passion for increasing awareness of the benefits of plasma protein therapies for people who are affected by a range of serious rare diseases, we welcome you as supporters.

  • Goal 1: A call for worldwide availability and access to safe and effective plasma protein therapies for all who need them
  • Goal 2: Supporting policies to improve patients’ access to therapies 
  • Goal 3: Highlighting patient options and the unique role of plasma protein therapies 
  • Goal 4: Highlighting the value, to patients and society, of plasma protein therapies 

A library of materials is available for your use in the resources section: posters, logo, videos, infographics, fact sheets, media background information.


”How Is Your Day?” is a global initiative that unites these people worldwide. It amplifies their voices and draws attention to the unique nature of plasma protein therapies. While treatment options (plasma-derived and their recombinant analogs) exist for most people with bleeding disorders, a vast majority of those living with life-threatening, chronic, and genetic diseases have no alternatives to these therapies. Additionally, unlike traditional pharmaceuticals, the source material for most plasma protein therapies is human plasma.

“How Is Your Day?” focuses on individuals who live with these rare diseases and highlights the life-saving difference that plasma protein therapies make in their lives. “How Is Your Day?” shares their stories to build awareness of these conditions and to ensure life-saving plasma protein therapies are available to all those who need them.

The manufacturing of most plasma protein therapies begins with the collection of donated human plasma from healthy, committed donors. This resource-intensive process takes 7-12 months – from donation to completion of the finished product.

Plasma is a necessary resource

Because each plasma donation only contains a small quantity of the proteins needed to produce a given therapy, there is an inherently finite supply of therapies. For example, about 130 donations are needed to provide enough Immunoglobulin to treat one person with a primary immunodeficiency disease for one year. Further, roughly 900 donations are needed to provide enough alpha-1 proteinase inhibitor to treat one person with alpha-1 antitrypsin deficiency for one year, and approximately 1,200 plasma donations are needed to treat one individual with hemophilia for one year.
“How Is Your Day?” supports the availability of, and access to, safe and effective plasma protein therapies for all who need them. The vast majority of plasma protein therapies are manufactured from high-quality source plasma collected from healthy compensated donors. We support policies that safeguard patients’ access to plasma protein therapies.

Unique therapies

Unlike many traditional pharmaceuticals, plasma protein therapies are non-interchangeable biologics that produce different therapeutic outcomes based on each patient’s individual characteristics.  Patients depend on access to all available therapies that best fit their clinical need.

 ”How is Your Day” is an initiative of the Plasma Protein Therapeutics Association 
147 Old Solomons Island Road, Suite 100 Annapolis, MD 21401 USA